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Nobivac® DHPPi is a live combination vaccine against canine distemper, canine infectious hepatitis caused by canine adenovirus type 1, canine adenovirus type 2 infections, canine parvovirus and canine parainfluenza. Each dose contains at least 104.0 DICT50 of canine distemper virus strain Onderstepoort, 104.0 DICT50 of canine adenovirus type 2 strain Manhattan LPV3, 107.0 DICT50 of canine parvovirus strain C154 and 105.5 DICT50 of canine parainfluenza virus strain Cornell. The vaccine is lyophilized in single-dose vials and contains stabilizers and trace antibiotics.
Active immunization of dogs against canine distemper, canine infectious hepatitis caused by canine adenovirus type 1, infections caused by canine adenovirus type 2, canine parvovirus and canine parainfluenza.
Nobivac® DHPPi is recommended to complete the basic vaccination schedule for puppies and for annual revaccination of adult dogs. Since vaccination with Nobivac® DHPPi is likely to be part of a broader program, the following recommendations are included:
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Alternatively, doses of up to 1 g can be administered by bolus intravenous injection over approximately 5 minutes. Limited safety data are available to support administration of a 2 g dose in adults by bolus intravenous injection.
In adults and adolescents with creatinine clearance less than 51 ml/min, the dose should be adjusted as indicated below. Data to support the application of these dose adjustments for a 2 g dose unit are limited.
In selecting meropenem to treat a patient, the appropriateness of using a carbapenem antibacterial agent should be considered based on factors such as the severity of infection, the prevalence of resistance to other suitable antibacterial agents, and the risk of selection of carbapenem-resistant bacteria.
Resistance to penemic antibiotics of Enterobacteriaceae, Pseudomonas aeruginosa, Acinetobacter spp. varies across the European Union. Prescribing is recommended taking into account the local prevalence of resistance of these bacteria to penemics.
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Having a medical home is very important. This ensures that you or your child has a doctor you know and trust for all of your medical needs. If for any reason you need to change your PCP, call Member Services at 1-877-220-6376 (Nueces) or 1-855-425-3247 (Hidalgo).
An emergency medical condition is one that manifests itself by acute symptoms of recent onset and of sufficient severity (including severe pain) that any prudent layperson, having a general knowledge of health and medicine, would reasonably believe the absence of immediate medical attention would cause:
If you and/or your child become ill during the night or on a weekend and cannot wait for medical care, call your PCP for advice. If you and/or your child have a fever or sore throat and you are not sure what to do, call your PCP’s office. Your PCP or another doctor is available by phone 24 hours a day, 7 days a week.
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Canine parvovirus is the main canine viral disease. It mainly affects puppies, producing alteration of the intestinal villi, clinically manifested as bloody and foul-smelling diarrhea, together with a deterioration of the general condition of the animal.
The prognosis is fatal without treatment. Therefore, a correct diagnosis and early treatment is necessary. Such treatment is based on a diet rich in liquids, together with intravenous water and electrolyte replacement.
The most frequent presentation is digestive, with viral hemorrhagic gastroenteritis; the virus infects intestinal cells (enterocytes) and replicates producing necrosis and cell death, the mechanism responsible for the symptoms.
Parvovirosis affects young canids from 6 weeks of age when they lose maternal immunity; it is infrequent in adult animals because they are already immunized by vaccination or subclinical infections. In addition, the pathogenesis of the virus requires the presence of molecular factors present only in cells in mitosis, so it is essential that the tissue to be infected is in proliferation (as in growth, or cells of the intestinal epithelium).